Characterization and optimization of apoptosis- and autophagy-modulating natural products and derivatives for the elimination of therapy-resistant tumor cells
Natural product/HDAC inhibitor-mediated modulation of immune responses and cytostatic-induced stress responses for resensitization of therapy-resistant tumors
Characterization of the mechanism of action and medicinal chemistry optimization of antimicrobial natural products
Nisin as a model system for overcoming lantibiotic resistance in bacterial pathogens
Active compounds, substance optimisation, molecular probes for target identification and target validation
Microorganisms, resistance mechanisms, target finding, immune modulation
Tumours, resistance mechanisms, target finding
Molecular Modelling
