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Wissenschaftliches Kolloquium

GRK2158 Scientific Colloquium

Complementary to the lecture series GRK2158 offers a scientific colloquium on current research topics in the fields of chemoresistance against microorganisms and tumors as well as immune modulation. To cover these topics external scientists will be invited to give a talk about their recent research activities.

The scientific colloquium is combined with the work-in-progress reports of the doctoral students in GRK2158.

Summer Semester 2021

The colloquia will take place as online meetings starting at 4:30 pm. The invitation link will be send by email.

Date Speakers Title
19.04.21 Progress Reports  
  Flaminia Mazzone Identification and characterization of new natural products with anti-microbial activity against Apicomplexa and multiresistant gram-negative rods (4MRGN)
  Laura Mayer Diversity-oriented synthesis of diaryl substituted heterocycles via sequential palladium catalysis
26.04.21 Progress Reports  
  Pablo Cea Structure based drug design against Nisin resistance systems
  Lars Seiffert Synthesis of small-molecule inhibitors of nisin resistance protein
10.05.21 Progress Reports  
  Julian Schliehe-Diecks Characterization of synergy and resistance traits of HSP90 and HDAC inhibitors in leukemic cell lines
  Fabian Fischer Development of chemosensitizing HDAC-Inhibitors and HDAC-PROTACs
17.05.21 Guest talk tba
07.06.21 Progress Reports  
  Korana Mudrovcic Targeting protein-protein interactions within the autophagy-inducing ULK1 complex for cancer therapy
  Annabelle Friedrich Targeting protein-protein interactions within the autophagy-inducing ULK1 complex for cancer therapy
14.06.21 Dr. Bert Klebl, Managing Director and Chief Scientific Officer of Lead Discovery Center GmbH, Dortmund, Germany tba
21.06.21 Progress Reports  
  Talea Knak Structural Optimization of Chlorflavonin – a natural compound with antimycobacterial activityancer therapy
  Ilka Hinxlage Identification of Novel Apoptotic Signaling Pathways for the Elimination of Therapy-Resistant Tumors
28.06.21 Elke Röhrdanz, Head of the Unit Reproductive and Genetic Toxicology, BfArM (Federal Institute for Drugs and Medical Devices) tba
05.07.21 Guest talk tba
12.07.21 Guest talk tba

Wintersemester 2020/2021

The colloquia will take place as online meetings starting at 4:30 pm. The invitation link will be send by email.

Date Speakers Title
02.11.2020 Dr. Sandra Maaß, University of Greifswald, Institute of Microbiology Proteomic Adaptation of Clostridioides difficile to Treatment with the Antimicrobial Peptide Nisin
16.11.2020 Prof. Dr. Maria Chiara Monti, Univerista’ degli Studi di Salerno, Italy, Pharmaceutical Department The role of functional proteomics in disclosing natural products targets
30.11.2020 Prof. Dr. Tanja Schneider, University Bonn, Pharmaceutical Microbiology Cell wall biosynthesis as a target for (novel) antibiotics
14.12.2020 Starting 12:30 Prof. Dr. Kui Zhu, China Agricultural University Beijing, China The discovery of membrane targeting antibiotics
18.01.2021 Prof. Dr. Tal Dagan, Genomic Microbiology Group, Institute of Microbiology, Christian-Albrechts-University Kiel Plasmid Darwinian fitness and its implications for antibiotic resistance evolution
25.01.2021 Prof. Dr. Daniel Hoffmann, University of Dusiburg Essen, Bioinformatics and Computational Biophysics Statistical practice in the life sciences: tragic co

Summer Semester 2020

The colloquia will take place as online meetings starting at 4:30 pm. The invitation link will be send by email.

Date Speakers Title
11.05.2020 Kai Stühler, Institute of Molecular Medicine I, Proteome Research, Düsseldorf Thermal Proteome Profiling and other methods
22.06.2020 Anika Christoffel, Head of In vivo Department, Pharmacelsus GmbH, Julia Przibilla, Head of In vitro Department, Pharmacelsus GmbH Preclinical in vitro and in vivo testing
06.07.2020 Christian Hertweck, Leibniz Institute for Natural Product Research and Infection Biology / Universtity of Jena Natural Product Biosynthesis in Underexplored Microbial Niches

Winter Semester 2019/20

The colloquia will take place in Building 25.22. Lecture Hall 5H starting at 4:30 pm.

Date Speakers Title
28.10.2019 Kick-Off Meeting  
11.11.2019 Prof. Dr. Ulrike Holzgrabe, University of Würzburg, Chair of Pharmaceutical and Medicinal Chemistry Lead structures from nature for antiinfective drugs
16.12.2019 Prof. Dr. Hans Kreipe, Hannover Medical School, Institute of Pathology Treating luminal breast cancer: is endocrine therapy sufficient or is additional chemotherapy needed because of endocrine resistance?
13.01.2020 Prof. Dr. Andrea Huwiler, University of Bern, Institute of Pharmacology The contribution of sphingosine kinases and S1P to renal fibrotic processes
03.02.2020 Prof. Dr. Markus Kalesse, Leibniz University Hannover, Institute of Organic Chemistry The synthetic road to natural products

Summer Semester 2019

The work-in-progress seminars will take place in Building 26.41. Lecture Hall 6H starting at 4:30 pm.

Date Speakers
15.04.2019 Work-In-Progress Seminar: Haiqian Yu (RG P. Proksch), Shabnam Shaneh Sazzadeh (RG K. Pfeffer)
29.04.2019 Work-In-Progress Seminar: Chenyin Wang (RG M. Kassack), Lisa Richter (RG S. Scheu)
13.05.2019 Work-In-Progress Seminar: Yodita Asfaha (RG T. Kurz), Jana van Stuijvenberg (RG G. Fritz)
17.06.2019 Work-In-Progress Seminar: Daniel Drießen (RG T.J.J. Müller), Christian Schrenk (RG M. Kassack)
01.07.2019 Work-In-Progress Seminar: David Bickel (RG H. Gohlke), Nam Michael Tran-Cong (RG P. Proksch)

Winter Semester 2018/2019

The scientific colloquia and the work-in-progress seminars will take place in Building 25.22. Lecture Hall 5H starting at 4:30 pm.

Date Speakers Title
15.10.2018 Presentation of CherryKuKess - Innovative drug development for difficult-to-treat cancers (Spin-off of the department of Gynecology and Obstetrics of University Hospital Düsseldorf  
22.10.2018 Work-In-Progress Seminar: Yodita Asfaha (RG T. Kurz), Shabnam Shaneh Sazzadeh (RG K. Pfeffer)  
29.10.2018 Debriefing of Symposium 2018  
05.11.2018 Work-In-Progress Seminar: Haiqian Yu (RG P. Proksch), Tino Seidemann (RG R. Kalscheuer)  
12.11.2018 Dr. RuAngelie Edrada-Ebel, Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK Using Analytical Data for Metabolic-guided Producation and Isolation of Bioactive Natural Products
19.11.2018 Work-In-Progress Seminar: David Schlütermann (RG B. Stork), Christian Schrenk (RG M. Kassack)  
26.11.2018 Dr. Alexander Birkmann, Head of Research, AiCuris Anti-Infective Cures GmbH Drug discovery in industry: Pritelivir, a non-nucleosidic inhibitor of herpes simplex virus
03.12.2018 Work-In-Progress Seminar: Hjördis Brückmann (RG H. Stark), David Bickel (RG H. Gohlke)  
10.12.2018 Dr. Dominic Hoepfner, Novartis Institutes for BioMedical Research, Chemical Biology & Therapeutics, Novartis Pharma AG Fishing for Compound Targets using Bar-coded Deletion Collections
17.12.2018 Prof. Dr. Bin-Gui Wang, Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China Chemical diversity of halogenated organic molecules from marine red algae
07.01.2019 Prof. Dr. Bernd Riedl, Vice President Medicinal Chemistry, Bayer AG Chemical postevolution of natural products in the field of antibacterial therapy
14.01.2019 Work-In-Progress Seminar: Marc Pflieger (RG T. Kurz), Annika Frank (RG H. Stark), Tino Seidemann (RG T. Kurz)  
21.01.2019 Dr. Bert Klebl, Managing Director and Chief Scientific Officer of Lead Discovery Center GmbH, Dortmund, Germany LDC – a (Proven) Model for Bridging Academia to “Pharmaceutical Industry”

Summer Semester 2018

The scientific colloquia and the work-in-progress seminars will take place in Building 26.41. Lecture hall 6H starting at 4:30 pm.

Date Speakers Title  
16.04.2018 Work-In-Progress Seminar: Haiqian Yu, Nam Tran-Cong, Yvonne Gröner    
07.05.2018 Work-In-Progress Seminar: Lisa Richter, Tino Seidemann, Fabian Stuhldreier    
28.05.2018 Prof. Dr. Andreas Kirschning, Institute of Organic Chemistry, Leibniz University Hannover Totally Synthetic: Learning from the synthetic chemist NATURE  
  Progress Reports: Daniel Drießen, Julia Sperlich    
04.06.2018 PD Dr. Zoe Waibler, Paul-Ehrlich-Institut, Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel Batch testing and batch release of immunological biomedicines in Germany  
11.06.2018 Work-In-Progress Seminar: Julian Greb, Julia Zaschke-Kriesche, Nicola Porta    
18.06.2018 Dr. Jan Bülle, Kutzenberger Wolff & Partner, Partner, Dipl. Chem., Patentanwalt, European Patent & Trademark Attorney Patent of drugs
02.07.2018 Work-In-Progress Seminar: David Schlütermann, Jana Deitersen    
09.07.2018 Prof. Dr. Werner Knöss, Federal Institute for Drugs and Medical Devices (BfArM), Head of Unit 44 Cannabis Agency, Head of Division Licensing 4, Complementary and Alternative Medicines and Traditional Medicines, Bonn, Germany Science and Regulatory Affairs - Plant Derived Drugs
16.07.2018 Work-In-Progress Seminar: Hjördis Brückmann, Jana van Stuijvenberg, David Bickel    

Winter Semester 2017/2018

The scientific colloquia and the work-in-progress seminars will take place in Building 25.22. Lecture Hall 5H starting at 4:30 pm.

Date Speakers Title
16.10.2017 PD Dr. Evi Stegmann, University of Tübingen, Interfaculty Institute of Microbiology and Infection Medicine (IMIT) (invited by S. Smits) Peptidoglycan modifications: Resistance and more?
  Progress Reports: Julia Zaschke-Kriesche (RG Smits)  
06.11.2017 Prof. Dr. Rebecca Wade, ZMBH Research Group Leader, University of Heidelberg (invited by H. Gohlke) Computational Mapping of Protein Binding Sites for Drug Discovery
  Progress Reports: Nicola Porta, David Bickel  
20.11.2017 Prof. Dr. Verena Jendrossek, Institute of Cell biology, University of Duisburg-Essen (invited by G. Fritz) Widening the therapeutic window: Biological approaches to optimization of radiotherapy
  Progress Reports: Jana van Stuijvenberg, Shabnam Shaneh Sazzadeh  
04.12.2017 Prof. Dr. Michael Gütschow, University of Bonn Cathepsin Inhibitors: From Peptides to Potential Cancer Therapeutics and Diagnostics
  Progress Reports: Annika Frank, Hjördis Brückmann  
18.12.2017 Prof. Dr. Wolfgang A. Schulz, Clinical Research Lab for Urology, University Medical Centre Düsseldorf Introduction to Cancer Epigenetics
  Progress Reports: Christian Schrenk, Chenyin Wang  
22.01.2018 Jun.-Prof. Dr. Finn Hansen, Institute of Pharmacy, University of Leipzig Rational design and diversity-oriented synthesis of selective histone deacetylase (HDAC) inhibitors for the epigenetic therapy of cancer
  Progress Reports: Yodita Asfaha, Marc Pflieger  

Summer Semester 2017

The scientific colloquia and the work-in-progress seminars will take place in

Building 26.41. Level U1/00 Lecture hall 6H starting at 4:00 pm.

The scientific colloquium on June 12th will start at 4:30 pm.

Date Speakers Title
08.05.2017 Prof. Dr. Nicole Teusch, TH Köln, Faculty of Applied Natural Sciences (invited by P. Proksch) Indolactam V analogs as inhibitors of proteinase activated receptor (PAR)2 in triple negative breast cancer
  Progress Reports: Mariam Moussa, Nam Tran-Cong, Haiqian Yu  
22.05.2017 Prof. Dr. Julia Bandow, Ruhr-University Bochum, Chair of Microbial Biology/ Group of Microbial Antibiotics Research (invited by R. Kalscheuer) Antibacterial Strategies
  Progress Reports: Yvonne Gröner, Tino Seidemann  
12.06.2017 4:30 pm Prof. Dr. Hans Reinke, Leibniz Research Institute for Environmental Medicine, Reinke research group: chronobiology and environmental medicine (invited by B. Stork) Crosstalk of Clock Gene Expression and Autophagy in Aging
  Progress Reports: Jana Deitersen, David Schlütermann  
26.06.2017 Dr. Justine Rudner, Institute of Cell Biology, University of Duisburg-Essen (invited by S. Wesselborg) New strategies to improve radiation therapy
  Progress Reports: Fabian Stuhldreier, Philip Böhler  
10.07.2017 Prof. Dr. Andreas Reichert, Institute of Biochemistry and Molecular Biology I, University Hospital Düsseldorf Mitochondrial quality control – how to sort out and dispose dysfunctional mitochondria
  Progress Reports: Anja Weber, Julian Greb  
24.07.2017 Dr. Hubertus Hochrein, Bavarian Nordic, München (invited by Stefanie Scheu) Fighting Infectious Diseases and Cancer with Poxviruses
  Progress Reports: Lisa Richter, Daniel Drießen  
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